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Almost every chronic illness known to humankind has been linked in some measure to free-radical-induced tissue damage, says Lise Alschuler, ND, FABNO, coauthor of The Definitive Guide to Cancer

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Regarding treatment strategies, it is suggested that the marked decrease in GPx1 expression may be the major mechanism of tumor sensitization to anthracyclines [93] and that GPx1 can partially inhibit doxorubicin-induced cell death-related signaling in breast cancer by interfering with the activation of the sphingomyelin-ceramide pathway [85]